What is it

A creatinine test is a measure of how well your kidneys are performing their job of filtering waste from your blood. Creatinine is a chemical compound left over from energy-producing processes in your muscles. Healthy kidneys filter creatinine out of the blood. Creatinine exits your body as a waste product in urine. Measurement of creatinine in your blood or urine provides clues to help your doctor determine how well the kidneys are working.

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Why it's done

Your doctor or other health care provider may order a creatinine test for the following reasons:

  • To make a diagnosis if you have signs or symptoms of kidney disease
  • To screen for kidney disease if you have diabetes, high blood pressure or other conditions that increase the risk of kidney disease
  • To monitor kidney disease treatment or progression
  • To monitor for side effects of drugs that may include kidney damage or altered kidney function
  • To monitor the function of a transplanted kidney

How is it done

A standard blood test is used to measure creatinine levels in your blood (serum creatinine). Your doctor may ask you not to eat (fast) overnight before the test. For a creatinine urine test, you may need to collect urine over 24 hours in containers provided by the clinic. For either test, you may need to avoid eating meat for a certain period before the test. If you take a creatine supplement, you’ll likely need to stop use.

For a serum creatinine test, a member of your healthcare team takes a blood sample by inserting a needle into a vein in your arm. For a urine test, you’ll need to provide a single sample in the clinic or collect samples at home over 24 hours and return them to the clinic.

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